Loss of FrmA leads to increased cell-cell adhesion and impaired multi-cellular development of Dictyostelium cells

@article{Patel2008LossOF,
  title={Loss of FrmA leads to increased cell-cell adhesion and impaired multi-cellular development of Dictyostelium cells},
  author={Hitesh Patel and Valerie G Brunton},
  journal={Cellular and Molecular Life Sciences},
  year={2008},
  volume={66},
  pages={145-155}
}
Cell-cell adhesion is a critical property of all multi-cellular organisms and its correct regulation is critical during development, differentiation, tissue building and maintenance, and many immune responses. The multi-talin-like FERM domain containing protein, FrmA, is required during starvation-induced multi-cellular development of Dictyostelium cells. Loss of FrmA leads to increased cell-cell adhesion and results in impaired multi-cellular development, slug migration and fruiting bodies… CONTINUE READING

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