Loss of Dopamine Transporters in Methamphetamine Abusers Recovers with Protracted Abstinence

@article{Volkow2001LossOD,
  title={Loss of Dopamine Transporters in Methamphetamine Abusers Recovers with Protracted Abstinence},
  author={N. Volkow and L. Chang and G. Wang and J. Fowler and D. Franceschi and M. Sedler and S. Gatley and E. Miller and R. Hitzemann and Y. Ding and J. Logan},
  journal={The Journal of Neuroscience},
  year={2001},
  volume={21},
  pages={9414 - 9418}
}
  • N. Volkow, L. Chang, +8 authors J. Logan
  • Published 2001
  • Psychology, Medicine
  • The Journal of Neuroscience
  • Methamphetamine is a popular drug of abuse that is neurotoxic to dopamine (DA) terminals when administered to laboratory animals. Studies in methamphetamine abusers have also documented significant loss of DA transporters (used as markers of the DA terminal) that are associated with slower motor function and decreased memory. The extent to which the loss of DA transporters predisposes methamphetamine abusers to neurodegenerative disorders such as Parkinsonism is unclear and may depend in part… CONTINUE READING
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