Loss of Deacetylation Activity of Hdac6 Affects Emotional Behavior in Mice

@article{Fukada2012LossOD,
  title={Loss of Deacetylation Activity of Hdac6 Affects Emotional Behavior in Mice},
  author={M. Fukada and A. Hanai and A. Nakayama and T. Suzuki and N. Miyata and R. Rodriguiz and W. Wetsel and T. Yao and Y. Kawaguchi},
  journal={PLoS ONE},
  year={2012},
  volume={7}
}
Acetylation is mediated by acetyltransferases and deacetylases, and occurs not only on histones but also on diverse proteins. Although histone acetylation in chromatin structure and transcription has been well studied, the biological roles of non-histone acetylation remain elusive. Histone deacetylase 6 (Hdac6), a member of the histone deacetylase (HDAC) family, is a unique deacetylase that localizes to cytoplasm and functions in many cellular events by deacetylating non-histone proteins… Expand
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