Loss of [3H]4-DAMP binding to muscarinic receptors in the orbitofrontal cortex of Alzheimer’s disease patients with psychosis

Abstract

Neuropsychiatric behaviours in Alzheimer’s disease (AD) patients have been associated with neocortical alterations of presynaptic cholinergic and muscarinic M2 receptor markers. In contrast, it is unclear whether non-M2 muscarinic receptors have a role to play in AD behavioural symptoms. To correlate the alterations of neocortical postsynaptic muscarinic… (More)
DOI: 10.1007/s00213-008-1124-9

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