Loss and atrophy of layer II entorhinal cortex neurons in elderly people with mild cognitive impairment.

@article{Kordower2001LossAA,
  title={Loss and atrophy of layer II entorhinal cortex neurons in elderly people with mild cognitive impairment.},
  author={Jeffrey H. Kordower and Yaping Chu and Glenn T. Stebbins and Steven DeKosky and Elizabeth J. Cochran and David A. Bennett and Elliott J. Mufson},
  journal={Annals of neurology},
  year={2001},
  volume={49 2},
  pages={202-13}
}
Layer II of the entorhinal cortex contains the cells of origin for the perforant path, plays a critical role in memory processing, and consistently degenerates in end-stage Alzheimer's disease. The extent to which neuron loss in layer II of entorhinal cortex is related to mild cognitive impairment without dementia has not been extensively investigated. We analyzed 29 participants who came to autopsy from our ongoing longitudinal study of aging and dementia composed of religious clergy… CONTINUE READING
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