Losartan and tempol treatments normalize the increased response to hydrogen peroxide in resistance arteries from hypertensive rats.

@article{GarcaRedondo2009LosartanAT,
  title={Losartan and tempol treatments normalize the increased response to hydrogen peroxide in resistance arteries from hypertensive rats.},
  author={Ana Bel{\'e}n Garc{\'i}a-Redondo and Ana Mar{\'i}a Flores Briones and Mar{\'i}a Soledad Avenda{\~n}o and Raquel Hernanz and M. Jes{\'u}s Gonz{\'a}lez Alonso and M. Gonz{\'a}lez Salaices},
  journal={Journal of hypertension},
  year={2009},
  volume={27 9},
  pages={
          1814-22
        }
}
OBJECTIVE To analyse the role of angiotensin II, via AT1 receptors, and oxidative stress in the mechanisms underlying the increased response to hydrogen peroxide (H2O2) of mesenteric resistance arteries from spontaneously hypertensive rats (SHRs). METHODS Arteries from normotensive and SHRs untreated or treated with the AT1 receptor antagonist, losartan (15 mg/kg per day, 12 weeks), or with the superoxide dismutase analogue, tempol (1 mmol/l, 17 days), were used. Arteries were mounted in… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-7 OF 7 CITATIONS

References

Publications referenced by this paper.

of this work was previously presented at the 30th Congress of the Spanish Society of Pharmacology

  • of this work was previously presented at the 30th Congress of the Spanish Society of Pharmacology
  • 2008

Similar Papers

Loading similar papers…