Lorazepam versus diazepam in the acute treatment of epileptic seizures and status epilepticus.

@article{Appleton1995LorazepamVD,
  title={Lorazepam versus diazepam in the acute treatment of epileptic seizures and status epilepticus.},
  author={Richard E Appleton and Angela Sweeney and Imti Choonara and Jenny Robson and Elizabeth Molyneux},
  journal={Developmental medicine and child neurology},
  year={1995},
  volume={37 8},
  pages={
          682-8
        }
}
Lorazepam was compared with diazepam for the treatment of acute convulsions and status epilepticus in 102 children in a prospective, open, 'odd and even dates' trial. Convulsions were controlled in 76 per cent of patients treated with a single dose of lorazepam and 51 per cent of patients treated with a single dose of diazepam. Significantly fewer patients treated with lorazepam required additional anticonvulsants to terminate the seizure. Respiratory depression occurred in 3 per cent of… CONTINUE READING
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