Loperamide, the “Poor Man’s Methadone”: Brief Review

@article{Stanciu2017LoperamideT,
  title={Loperamide, the “Poor Man’s Methadone”: Brief Review},
  author={Cornel N Stanciu and Samantha A. Gnanasegaram},
  journal={Journal of Psychoactive Drugs},
  year={2017},
  volume={49},
  pages={18 - 21}
}
ABSTRACT Loperamide is widely available as an inexpensive, over-the-counter remedy commonly used for management of diarrhea. Although an opioid, at therapeutic doses it acts primarily on the gastrointestinal tissues; however, larger than recommended amounts facilitate central nervous system (CNS) penetration. Such high doses of loperamide have recently gained popularity among users of opioids to manage withdrawal symptomatology and, less frequently, to achieve psychoactive effects. Chronic… 
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