Looking into live cells with in-cell NMR spectroscopy.

@article{Selenko2007LookingIL,
  title={Looking into live cells with in-cell NMR spectroscopy.},
  author={Philipp Selenko and Gerhard Wagner},
  journal={Journal of structural biology},
  year={2007},
  volume={158 2},
  pages={
          244-53
        }
}
In-cell NMR spectroscopy has gained recent popularity since it provides means to analyze the conformational and functional properties of proteins inside living cells and at atomic resolution. High-resolution in-cell NMR spectroscopy was originally established in bacterial cells and based on a rationale that relies on protein over-expression and sample analysis within the same cellular environment. Here, we review in-cell NMR approaches in Xenopus laevis oocytes and evaluate potential future… CONTINUE READING

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