Looking for the minimum common denominator in haem-copper oxygen reductases: towards a unified catalytic mechanism.

@article{Pereira2008LookingFT,
  title={Looking for the minimum common denominator in haem-copper oxygen reductases: towards a unified catalytic mechanism.},
  author={M Manuela A Pereira and Filipa L. Sousa and Andreia F. Verissimo and Miguel Teixeira},
  journal={Biochimica et biophysica acta},
  year={2008},
  volume={1777 7-8},
  pages={929-34}
}
Haem-copper oxygen reductases are transmembrane protein complexes that reduce dioxygen to water and pump protons across the mitochondrial or periplasmatic membrane, contributing to the transmembrane difference of electrochemical potential. Seven years ago we proposed a classification of these enzymes into three different families (A, B and C), based on the amino acid residues of their proton channels and amino acid sequence comparison, later supported by the so far identified characteristics of… CONTINUE READING

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