Looking back to the embryo: defining transcriptional networks in adult myogenesis

@article{Parker2003LookingBT,
  title={Looking back to the embryo: defining transcriptional networks in adult myogenesis},
  author={M. Parker and P. Seale and M. Rudnicki},
  journal={Nature Reviews Genetics},
  year={2003},
  volume={4},
  pages={497-507}
}
Skeletal muscle has an intrinsic capacity for regeneration following injury or exercise. The presence of adult stem cells in various tissues with myogenic potential provides new opportunities for cell-based therapies to treat muscle disease. Recent studies have shown a conserved transcriptional hierarchy that regulates the myogenic differentiation of both embryonic and adult stem cells. Importantly, the molecules and signalling pathways that induce myogenic determination in the embryo might be… Expand
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