Looking Beyond Respiratory Cultures: Microbiome-Cytokine Signatures of Bacterial Pneumonia and Tracheobronchitis in Lung Transplant Recipients.

@article{Shankar2016LookingBR,
  title={Looking Beyond Respiratory Cultures: Microbiome-Cytokine Signatures of Bacterial Pneumonia and Tracheobronchitis in Lung Transplant Recipients.},
  author={Jyoti Shankar and Minh Hong Nguyen and Mar{\'i}a del Mar Segu{\'i} Crespo and Eun Jeong Kwak and Sarah K Lucas and Kevin J McHugh and Stephanie Mounaud and John F Alcorn and Joseph Pilewski and Norihisa Shigemura and Jay K Kolls and William C. Nierman and Cornelius J. Clancy},
  journal={American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons},
  year={2016},
  volume={16 6},
  pages={1766-78}
}
Bacterial pneumonia and tracheobronchitis are diagnosed frequently following lung transplantation. The diseases share clinical signs of inflammation and are often difficult to differentiate based on culture results. Microbiome and host immune-response signatures that distinguish between pneumonia and tracheobronchitis are undefined. Using a retrospective study design, we selected 49 bronchoalveolar lavage fluid samples from 16 lung transplant recipients associated with pneumonia (n = 8… CONTINUE READING

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