# Looking Back on the Discovery of α-Bungarotoxin

@article{Chang1999LookingBO,
title={Looking Back on the Discovery of $\alpha$-Bungarotoxin},
author={C.C. Chang},
journal={Journal of Biomedical Science},
year={1999},
volume={6},
pages={368 - 375}
}
• C.C. Chang
• Published 22 October 1999
• Biology
• Journal of Biomedical Science
This review is a personal narration by a retiring pharmacologist from Taiwan who looks back at his discovery of α-bungarotoxin from the historical perspective of Taiwan during the last 50 years, with accounts of his experiences and his efforts to overcome hardship. How the α-toxin was isolated and characterized as an irreversible specific nicotinic acetylcholine (ACh) receptor antagonist, and how it subsequently became a useful experimental probe are presented here. The dilemma of…
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