Longitudinally Extensive Varicella-Zoster Virus Myelitis in a Patient With Multiple Sclerosis

  title={Longitudinally Extensive Varicella-Zoster Virus Myelitis in a Patient With Multiple Sclerosis},
  author={Juan Pablo Cuello and J. Viguera Romero and Fernando de Ory and Clara de Andr{\'e}s},
Study Design. Case report. Objective. To report this rare varicella-zoster virus (VZV) complication in a patient with multiple sclerosis. Summary of Background Data. Longitudinally extensive transverse myelitis is a spinal cord lesion that extends over 3 or more vertebral segments. A common feature in neuromyelitis optica, longitudinally extensive transverse myelitis can also occur in several other diseases. Methods. A 15-year-old boy with relapsing-remitting multiple sclerosis, who has been… 

Transverse myelitis caused by varicella-zoster

A 28-year-old immunocompetent man, who presented with fever, rash and acute-onset spastic paraparesis with bladder involvement, was diagnosed with acute primary disseminated VZV infection with parainfectious transverse myelitis and treated with intravenous acyclovir and steroids, with which he improved significantly.

Varicella‐zoster virus encephalomyelitis with a prominent demyelinating component

This case represents a rare example of VZV encephalomyelitis presenting with a predominantly demyelinating, “multiple sclerosis‐like” pathology and the clinical and histopathologic findings and relevant literature are presented and discussed.

Neurological complications of varicella zoster virus reactivation.

Awareness of the expanding spectrum of neurological complications caused by VZV reactivation with and without rash will improve diagnosis and treatment.

Infections of the Spinal Cord

Infectious myelopathies can be caused by viral, bacterial, fungal, and parasitic agents and the most common causes are reviewed.

Diverse clinical manifestations caused by varicella-zoster virus reactivation

Diverse clinical manifestations caused by VZV reactivation, particular without skin rash, are reviewed.

Neurological complications of varicella zoster virus reactivation opyright

Varicella zoster virus (VZV) reactivation results in zoster, which may be complicated by postherpetic neuralgia, myelitis, meningoencephalitis, and VZV vasculopathy, is reviewed.

Varicella Zoster Virus Induces Nuclear Translocation of the Neurokinin-1 Receptor, Promoting Lamellipodia Formation and Viral Spread in Spinal Astrocytes

A novel, subP-independent, proviral function of nuclear NK-1R associated with lamellipodia formation and viral spread that is distinct from subP -induced NK- 1R cell membrane/cytoplasmic localization without lamellippedia formation is identified.

Approach to Neurologic Complications in the Immunocompromised Patient.

This review provides a chief complaint-based approach to the clinical presentations and diagnosis of both infectious and noninfectious complications particular to immunocompromised patients.

Longitudinal Extensive Transverse Myelitis due to Varicella Zoster Virus Infection in a Patient without Immunodeficiency: A Case Report

Varicella zoster virüs (VZV), özellikle suçiçeği ve herpes zoster hastalığının etiyolojisinde rol oynayan, herpes ailesine mensup bir virüstür ganlionunda latent kalabilen bu virüSün reaktive olmasıyla meydana gelmektedir.

Infections of the spine and spinal cord.



Herpes zoster myelitis.

The protracted evolution in many cases and the pathologically documented direct viral infection of the spinal cord provide a rational basis for the use of antiviral therapy in preventing or attenuating the evolving myelopathy.

Longitudinal extensive transverse myelitis—it's not all neuromyelitis optica

The signs and symptoms that suggest various etiologies and differential diagnoses of LETM are described, and illustrated by educational case studies.

Varicella-Zoster virus infections of the nervous system: clinical and pathologic correlates.

Varicella-zoster virus infects a wide variety of cell types in the central and peripheral nervous system, explaining the diversity of clinical disorders associated with the virus.

Fatal varicella‐zoster virus meningoradiculitis without skin involvement

A 77‐year‐old man with T‐cell lymphoma developed an acute fatal meningoradiculitis of cranial nerve roots and cauda equina, pathologically and virologically confirmed to be caused by varicella‐zoster

Varicella-Zoster Virus Infections of the Nervous System

The pathologic correlates of the neurologic complications of VZV infection, as well as current methods for detecting viral infections, are discussed and presented in pictorial format for the practicing pathologist.

Diagnosis of neurological herpesvirus infections: real time PCR in cerebral spinal fluid analysis.

Analysis of CSF from 146 patients with acute meningitis or meningoencephalitis and 9 with "other neurological disorders" found HHVs DNA was detected in 52 of 155 analyzed samples, and two patients with Guillain-Barré syndrome had HCMV and one showed HHV6 positivity.

Recommendations for the management of herpes zoster.

The results of controlled trials and the clinical experience of the authors support the use of acyclovir, brivudin (where available), famciclovir, and valacy Clovir as first-line antiviral therapy for the treatment of patients with HZ.

Diagnosis of neurological herpes virus infections : real time PCR in cerebral spinal fl uid analy

  • New Microbiol
  • 2009