Longitudinal surveillance of Haemophilus influenzae isolates from pediatric patients with meningitis throughout Japan, 2000-2011.

@article{Ubukata2013LongitudinalSO,
  title={Longitudinal surveillance of Haemophilus influenzae isolates from pediatric patients with meningitis throughout Japan, 2000-2011.},
  author={Kimiko Ubukata and Naoko Chiba and Miyuki Morozumi and Satoshi Iwata and Keisuke Sunakawa},
  journal={Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy},
  year={2013},
  volume={19 1},
  pages={34-41}
}
In Japan, β-lactamase-nonproducing, ampicillin-resistant organisms have been evident among Haemophilus influenzae type b (Hib) isolates since 2000, when no appropriate vaccine had been approved. We therefore performed molecular analysis of agents causing H. influenzae meningitis nationwide over the following 10 years. Some 285 institutions have participated in surveillance since 2000. The capsular type and resistance genes of 1,353 isolates and 23 cerebrospinal fluid samples from pediatric… CONTINUE READING

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