Longitudinal study of thyroid function in Down's syndrome in the first two decades.

@article{Gibson2005LongitudinalSO,
  title={Longitudinal study of thyroid function in Down's syndrome in the first two decades.},
  author={Perry A. Gibson and Richard Newton and Kathryn Selby and David Anthony Price and Kirsten Leyland and G Michael Addison},
  journal={Archives of disease in childhood},
  year={2005},
  volume={90 6},
  pages={574-8}
}
AIMS AND METHODS Thyroid function tests were initially carried out on 122 children with Down's syndrome aged 6-14 years and then repeated four to six years later in 103 adolescents (85% of the group of 122) when they were aged 10-20 years (median 14.4 years). At the second test two were hypothyroid and two with isolated raised thyroid stimulating hormone (IR-TSH) were receiving thyroxine. RESULTS At the first test there were 98 (80%) euthyroid children: 83 were retested and four (5%) had IR… CONTINUE READING