Longitudinal studies of ischemic penumbra by using 18F-FDG PET and MRI techniques in permanent and transient focal cerebral ischemia in rats

@article{Sobrado2011LongitudinalSO,
  title={Longitudinal studies of ischemic penumbra by using 18F-FDG PET and MRI techniques in permanent and transient focal cerebral ischemia in rats},
  author={M{\'o}nica Sobrado and M. Delgado and E. Fern{\'a}ndez-Valle and L. Garc{\'i}a-Garc{\'i}a and M. Torres and Jos{\'e} S{\'a}nchez-Prieto and J. Vivancos Mora and R. Manzanares and M. A. Moro and Miguel A. Pozo and Ignacio Lizasoain},
  journal={NeuroImage},
  year={2011},
  volume={57 1},
  pages={45-54}
}
At present, the goal of stroke research is the identification of a potential recoverable tissue surrounding the ischemic core, suggested as ischemic penumbra, with the aim of applying a treatment that attenuates the growth of this area. Our purpose was to determine whether a combination of imaging techniques, including (18)F-FDG PET and MRI could identify the penumbra area. Longitudinal studies of (18)F-FDG PET and MRI were performed in rats 3 h, 24 h and 48 h after the onset of ischemia. A… CONTINUE READING