Longitudinal studies of cognitive, functional and behavioural change in patients with Alzheimer's disease.

@article{Mohs2000LongitudinalSO,
  title={Longitudinal studies of cognitive, functional and behavioural change in patients with Alzheimer's disease.},
  author={Richard C. Mohs and James Schmeidler and Muhammedullah Aryan},
  journal={Statistics in medicine},
  year={2000},
  volume={19 11-12},
  pages={1401-9}
}
This paper reviews data on the natural history of symptoms in patients with Alzheimer's disease (AD) and describes some of the problems encountered in analysing longitudinal data in this population. Data on cognition, functional ability and psychiatric or behavioural symptoms have all been obtained from AD patients. Because of attrition, the length of follow-up is not uniform for all patients and neither is the frequency of evaluation. Furthermore, patients enter longitudinal studies with a… CONTINUE READING