Longitudinal pulmonary status of cystic fibrosis children with meconium ileus.

@article{Li2004LongitudinalPS,
  title={Longitudinal pulmonary status of cystic fibrosis children with meconium ileus.},
  author={Zhanhai Li and Huichuan J Lai and Michael R. Kosorok and Anita Laxova and Michael J. Rock and Mark L. Splaingard and Philip M. Farrell},
  journal={Pediatric pulmonology},
  year={2004},
  volume={38 4},
  pages={277-84}
}
Although meconium ileus (MI) is the earliest manifestation of cystic fibrosis (CF), and is associated with poorer growth, the longitudinal pulmonary progression of CF children with MI is not clear. To test the hypothesis that MI is associated with worse pulmonary outcomes, we prospectively compared from diagnosis to 12 years of age 32 CF children with MI to 50 CF children without MI who were diagnosed during early infancy through neonatal screening. Pulmonary outcome measures included… CONTINUE READING