Longitudinal non-invasive proton NMR spectroscopy measurement of vitreous lactate in a rabbit model of ocular hypertension.
@article{Ngumah2006LongitudinalNP, title={Longitudinal non-invasive proton NMR spectroscopy measurement of vitreous lactate in a rabbit model of ocular hypertension.}, author={Q. Ngumah and S. Buchthal and R. Dacheux}, journal={Experimental eye research}, year={2006}, volume={83 2}, pages={ 390-400 } }
To determine whether vitreous lactate concentrations are correlated with intraocular pressure (IOP) rise, retinal ganglion cell (RGC) damage, and nerve fiber layer (NFL) thickness decrease in a rabbit model of ocular hypertension. Also, to learn whether proton nuclear magnetic resonance ((1)H-NMR) spectroscopy can provide sequential, non-invasive in vivo measurements of vitreous lactate. Intra-anterior chamber injections of 20-mum latex beads were used to impede aqueous drainage in New Zealand… CONTINUE READING
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References
SHOWING 1-10 OF 22 REFERENCES
Non‐invasive measurement of steady‐state vitreous lactate concentration
- Chemistry, Medicine
- NMR in biomedicine
- 1994
- 28
Experimental glaucoma in the primate induced by latex microspheres
- Medicine
- Journal of Neuroscience Methods
- 2001
- 79
Blood flow and glucose consumption in the optic nerve, retina and brain: effects of high intraocular pressure.
- Chemistry, Medicine
- Experimental eye research
- 1985
- 59
Nondestructive Measurement of Retinal Glucose Transport and Consumption In Vivo Using NMR Spectroscopy
- Chemistry, Medicine
- Journal of neurochemistry
- 1995
- 10
Enzymatic histochemistry of retina with experimental intraocular pressure elevation in rabbits
- Biology, Medicine
- Journal of Tongji Medical University
- 2008
- 1
Intraocular dynamics of lactic acid in the rabbit.
- Chemistry, Medicine
- Investigative ophthalmology
- 1972
- 14
- PDF
Comparison of three tonometers for measuring intraocular pressure in rabbits.
- Medicine
- Investigative ophthalmology & visual science
- 1996
- 55
The physiology and pathophysiology of intraocular fluids.
- Biology, Medicine
- Experimental eye research
- 1977
- 51
Measurement of rabbit intraocular pressure with the Tono-Pen.
- Medicine
- Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde
- 1995
- 17