Longitudinal neuropsychological assessment in pediatric multiple sclerosis.

  title={Longitudinal neuropsychological assessment in pediatric multiple sclerosis.},
  author={William S Macallister and Christopher C Christodoulou and Maria Giovanna Milazzo and Lauren B. Krupp},
  journal={Developmental neuropsychology},
  volume={32 2},
Although Multiple Sclerosis (MS) occurring in childhood and adolescence has received increasing attention in recent years, the impact of the disease on cognitive function in this subgroup remains poorly understood. It has been posited that children and adolescents with MS may be particularly susceptible to cognitive dysfunction because the pathological processes, including inflammation, blood brain barrier breakdown, and demyelination, occur concurrently with ongoing myelination. Early work has… CONTINUE READING