Longitudinal measures of cholinergic forebrain atrophy in the transition from healthy aging to Alzheimer's disease.

@article{Grothe2013LongitudinalMO,
  title={Longitudinal measures of cholinergic forebrain atrophy in the transition from healthy aging to Alzheimer's disease.},
  author={Michel J. Grothe and Helmut Heinsen and Stefan J. Teipel},
  journal={Neurobiology of aging},
  year={2013},
  volume={34 4},
  pages={1210-20}
}
Recent evidence from cross-sectional in vivo imaging studies suggests that atrophy of the cholinergic basal forebrain (BF) in Alzheimer's disease (AD) can be distinguished from normal age-related degeneration even at predementia stages of the disease. Longitudinal study designs are needed to specify the dynamics of BF degeneration in the transition from normal aging to AD. We applied recently developed techniques for in vivo volumetry of the BF to serial magnetic resonance imaging scans of 82… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 48 extracted citations

Longitudinal progression of grey matter atrophy morphological characteristics in MCI patients

2013 IEEE International Conference on Medical Imaging Physics and Engineering • 2013
View 4 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…