Longitudinal measurement of plasma homovanillic acid levels in schizophrenic patients. Correlation with psychosis and response to neuroleptic treatment.

@article{Pickar1986LongitudinalMO,
  title={Longitudinal measurement of plasma homovanillic acid levels in schizophrenic patients. Correlation with psychosis and response to neuroleptic treatment.},
  author={David Pickar and Richard S. LaBarca and A R Doran and Owen M. Wolkowitz and Alec Roy and Alan Breier and Markku Linnoila and Steven M Paul},
  journal={Archives of general psychiatry},
  year={1986},
  volume={43 7},
  pages={669-76}
}
The plasma levels of homovanillic acid (HVA), a major circulating dopamine (DA) metabolite, were measured in schizophrenic patients during five weeks each of double-blind placebo-controlled neuroleptic treatment (N = 16) and withdrawal (N = 11). Both neuroleptic treatment and withdrawal were associated with time-dependent changes in the plasma levels of HVA… CONTINUE READING