Longitudinal investigation of adenovirus 36 seropositivity and human obesity: the Cardiovascular Risk in Young Finns Study

@article{Sabin2015LongitudinalIO,
  title={Longitudinal investigation of adenovirus 36 seropositivity and human obesity: the Cardiovascular Risk in Young Finns Study},
  author={Matthew Allen Sabin and David Burgner and Richard L Atkinson and Z Pei-Lun Lee and Costan G Magnussen and May Cheung and Mika K{\"a}h{\"o}nen and Terho Lehtim{\"a}ki and Eero J. Jokinen and Tomi T Laitinen and Nina Hutri-K{\"a}h{\"o}nen and Jorma S. A. Viikari and Markus Juonala and Olli T. Raitakari},
  journal={International Journal of Obesity},
  year={2015},
  volume={39},
  pages={1644-1650}
}
Background/Objectives:Adenovirus-36 (Adv-36) infection is associated with exaggerated adipogenesis in cell culture and the development of obesity in animal models and humans, but a causal relationship remains unproven. Our objective was to determine whether serological evidence of Adv-36 infection in childhood and/or adulthood is associated with adult obesity.Subjects/Methods:Paired plasma concentrations of Adv-36 antibodies were measured by a novel enzyme-linked immunosorbent assay in a… CONTINUE READING