Longitudinal in vivo microcomputed tomography of mouse lungs: No evidence for radiotoxicity.

  title={Longitudinal in vivo microcomputed tomography of mouse lungs: No evidence for radiotoxicity.},
  author={Greetje Vande Velde and Ellen De Langhe and Jennifer Poelmans and Peter Bruyndonckx and Emiliano D'Agostino and Erik Verbeken and Ria Bogaerts and Rik Lories and Uwe Himmelreich},
  journal={American journal of physiology. Lung cellular and molecular physiology},
  volume={309 3},
Before microcomputed tomography (micro-CT) can be exploited to its full potential for longitudinal monitoring of transgenic and experimental mouse models of lung diseases, radiotoxic side effects such as inflammation or fibrosis must be considered. We evaluated dose and potential radiotoxicity to the lungs for long-term respiratory-gated high-resolution micro-CT protocols. Free-breathing C57Bl/6 mice underwent four different retrospectively respiratory gated micro-CT imaging schedules of… 

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  • D. Clark, C. Badea
  • Physics, Medicine
    Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics
  • 2014
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