Longitudinal follow up of elevated pulmonary artery pressures in children with sickle cell disease.

@article{Pashankar2009LongitudinalFU,
  title={Longitudinal follow up of elevated pulmonary artery pressures in children with sickle cell disease.},
  author={Farzana Pashankar and Judith Carbonella and Alia Bazzy-Asaad and Alan Friedman},
  journal={British journal of haematology},
  year={2009},
  volume={144 5},
  pages={736-41}
}
Elevated pulmonary artery pressures (PAP) occur in approximately 30% of children with sickle cell disease. In adults, pulmonary hypertension is significantly associated with mortality. There are no data on the long term significance in children. Nineteen children with SS/Sbeta(0) thalassaemia had elevated PAP, defined as tricuspid regurgitant jet velocity (TRV) > or =2.5 m/s on screening echocardiograms. They were prospectively followed for 23 months (range 19-31 months). Patients with initial… CONTINUE READING