Longitudinal follow-up of bone density and body composition in children with precocious or early puberty before, during and after cessation of GnRH agonist therapy.

Abstract

We studied bone mineral density (BMD), bone metabolism, and body composition in 47 children with central precocious puberty (n = 36) or early puberty (n = 11) before, during, and after cessation of GnRH agonist. Bone density and body composition were measured with dual energy x-ray absorptiometry and expressed as SD scores. Bone age and biochemical… (More)

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@article{Sluis2002LongitudinalFO, title={Longitudinal follow-up of bone density and body composition in children with precocious or early puberty before, during and after cessation of GnRH agonist therapy.}, author={Inge M. van der Sluis and Annemieke M. Boot and Eric P. Krenning and Stenvert L. S. Drop and Sabine M P F de Muinck Keizer-Schrama}, journal={The Journal of clinical endocrinology and metabolism}, year={2002}, volume={87 2}, pages={506-12} }