Longitudinal follow-up of bipolar disorder in women with premenstrual exacerbation: findings from STEP-BD.

@article{Dias2011LongitudinalFO,
  title={Longitudinal follow-up of bipolar disorder in women with premenstrual exacerbation: findings from STEP-BD.},
  author={Rodrigo da Silva Dias and Beny Lafer and Cibele M. Russo and Alessandro Del Debbio and Andrew A. Nierenberg and Gary S. Sachs and Hadine Joffe},
  journal={The American journal of psychiatry},
  year={2011},
  volume={168 4},
  pages={
          386-94
        }
}
OBJECTIVE The impact of hormonal fluctuation during the menstrual cycle on the course of bipolar disorder is poorly understood. The authors determined the course of illness and time to relapse of bipolar disorder in prospectively followed women with premenstrual exacerbation. METHOD Participants were 293 premenopause-age women with bipolar disorder who were followed prospectively for 1 year as part of the Systematic Treatment Enhancement Program for Bipolar Disorder. Frequency of mood… CONTINUE READING

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