Longitudinal evaluation of diagnostics in experimentally infected young calves during subclinical and clinical paratuberculosis.

@article{Mortier2015LongitudinalEO,
  title={Longitudinal evaluation of diagnostics in experimentally infected young calves during subclinical and clinical paratuberculosis.},
  author={Rienske A R Mortier and H W Barkema and K Orsel and Gregory P Muench and Janet M Bystrom and Oscar Illanes and Jeroen De Buck},
  journal={The Canadian veterinary journal = La revue veterinaire canadienne},
  year={2015},
  volume={56 12},
  pages={1266-70}
}
Five calves were inoculated orally at 2 weeks of age with a dose of 5 × 10(9) colony-forming units of Mycobacterium avium subspecies paratuberculosis (MAP) on 2 consecutive days. Two calves developed clinical Johne's disease at 12 and 16 months of age after being consistently positive for MAP on fecal culture and antibody enzyme-linked immunosorbent assay… CONTINUE READING