Longitudinal evaluation of both morphologic and functional changes in the same individuals with Alzheimer's disease.

@article{Matsuda2002LongitudinalEO,
  title={Longitudinal evaluation of both morphologic and functional changes in the same individuals with Alzheimer's disease.},
  author={Hiroshi Matsuda and Noriyuki Kitayama and Takashi Ohnishi and Takashi Asada and Seigo Nakano and Shigeki Sakamoto and Etsuko Imabayashi and Asako Katoh},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={2002},
  volume={43 3},
  pages={304-11}
}
UNLABELLED Morphologic and functional imaging studies have not always given concordant results about brain areas showing atrophic changes and reduced flow or metabolism in Alzheimer's disease (AD). The aim of this study was to determine the initial abnormality and the longitudinal changes in both morphologic and functional measurements for the same individuals with AD. METHODS We investigated 15 patients with mild AD and 25 age-matched healthy volunteers. The AD patients underwent both MRI… CONTINUE READING
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