Longitudinal decline of the neuronal marker N-acetyl aspartate in Alzheimer's disease.

@article{Adalsteinsson2000LongitudinalDO,
  title={Longitudinal decline of the neuronal marker N-acetyl aspartate in Alzheimer's disease.},
  author={Elfar Adalsteinsson and Edith V. Sullivan and Natalia Kleinhans and Daniel Mark Spielman and Adolf Pfefferbaum},
  journal={Lancet},
  year={2000},
  volume={355 9216},
  pages={1696-7}
}
In patients with Alzheimer's disease, but not in health controls, longitudinal magnetic resonance spectroscopy shows a striking decline in the neuronal marker, N-acetyl aspartate, despite little decline in underlying grey-matter volume. 

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