Longitudinal changes in cortisol secretion and conversion to psychosis in at-risk youth.

@article{Walker2010LongitudinalCI,
  title={Longitudinal changes in cortisol secretion and conversion to psychosis in at-risk youth.},
  author={Elaine F. Walker and Patricia A. Brennan and Michelle L. Esterberg and Joy Lynn Brasfield and Brad Pearce and Michael Compton},
  journal={Journal of abnormal psychology},
  year={2010},
  volume={119 2},
  pages={401-8}
}
Elevations in hypothalamic-pituitary-adrenal (HPA) axis activity have been implicated in the origins and exacerbation of mental disorders. Several lines of investigation suggest HPA activity, indexed by increased cortisol, is elevated in patients with schizophrenia and other psychotic disorders. This study examined the relation of cortisol levels and longitudinal changes with psychotic outcomes in at-risk adolescents. Participants were 56 adolescents who met risk criteria for psychosis, namely… CONTINUE READING
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