Longitudinal assessment of Integra in primary burn management: a randomized pediatric clinical trial.

@article{Branski2007LongitudinalAO,
  title={Longitudinal assessment of Integra in primary burn management: a randomized pediatric clinical trial.},
  author={Ludwik K. Branski and David N . Herndon and Clifford B Pereira and Ronald P. Mlcak and Mario M Celis and Jong Ok Lee and Arthur P. Sanford and William B. Norbury and Xiao-Jun Zhang and Marc Gerhard Jeschke},
  journal={Critical care medicine},
  year={2007},
  volume={35 11},
  pages={2615-23}
}
BACKGROUND Early excision with autograft-allograft closure is standard in severe burn management. Cadaver skin is associated with risks such as antigenicity, infection, and limited availability and shelf life. Previous studies have shown that Integra is safe to use in burns of <20% total body surface area. However, the suitability of its use in large burns (>50% total body surface area), its effects on postburn hypermetabolism, and the long-term cosmetic and functional results have not yet been… CONTINUE READING

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