Longitudinal analysis of cartilage T2 relaxation times and joint degeneration in African American and Caucasian American women over an observation period of 6 years - data from the Osteoarthritis Initiative.

@article{Kretzschmar2016LongitudinalAO,
  title={Longitudinal analysis of cartilage T2 relaxation times and joint degeneration in African American and Caucasian American women over an observation period of 6 years - data from the Osteoarthritis Initiative.},
  author={Martin Kretzschmar and Ursula R. Heilmeier and Andrew Yu and G. Britto Joseph and Felix Liu and M Solka and Charles E Mcculloch and M. C. Nevitt and Thomas M. Link},
  journal={Osteoarthritis and cartilage},
  year={2016},
  volume={24 8},
  pages={1384-91}
}
OBJECTIVES To investigate the change in cartilage T2 values and structural degeneration in knee joints over 72 months in women of African American (AA) vs Caucasian American (CA) ethnicity. METHODS Knee 3T magnetic resonance imaging (MRIs) from baseline, 24, 48 and 72 months visits of 100 AA and 100 CA women from the Osteoarthritis Initiative (OAI) were assessed for cartilage T2 values and whole-organ magnetic resonance imaging (WORMS) score. Subjects were pair-matched by age, body mass index… CONTINUE READING

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Cartilage , meniscus and BMEP scores tended to increase in both groups during follow up , but rates of change did not differ by ethnicity .
We compared the rate of change in whole knee cartilage T2 values and WORMS cartilage , bone marrow edema pattern ( BMEP ) and meniscus scores between the two ethnic groups using mixed random effects models .
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