Longitudinal Study of Serum Lipids and Liver Enzymes in Workers With Occupational Exposure to Ammonium Perfluorooctanoate

  title={Longitudinal Study of Serum Lipids and Liver Enzymes in Workers With Occupational Exposure to Ammonium Perfluorooctanoate},
  author={Carine J Sakr and Robin C. Leonard and Kim H. Kreckmann and Martin D Slade and Mark R. Cullen},
  journal={Journal of Occupational and Environmental Medicine},
  • C. SakrR. Leonard M. Cullen
  • Published 1 August 2007
  • Medicine, Biology
  • Journal of Occupational and Environmental Medicine
Objective: To examine the relationship between serum perfluorooctanoate (PFOA), a biomarker of ammonium perfluorooctanoate exposure, and lipids and liver enzymes. Methods: We conducted a longitudinal study on 454 workers and used mixed models to examine the relationship between serum PFOA and lipids and liver enzymes. Results: One part per million (ppm) increase in serum PFOA was associated with a 1.06 mg/dL increase in total cholesterol, but was not associated with changes in triglycerides or… 

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