Longitudinal MRI and neuropsychological assessment of patients with clinically isolated syndrome

  title={Longitudinal MRI and neuropsychological assessment of patients with clinically isolated syndrome},
  author={Tomas Uher and Jana Blahova-Dusankova and D. Hor{\'a}kov{\'a} and Niels P Bergsland and Michaela T{\'y}blov{\'a} and Ralph H. B. Benedict and Tomas Kalincik and Deepa Ramasamy and Z Seidl and Jesper Hagermeier and M Vaneckova and J Krasensky and Eva Kubala Havrdov{\'a} and Robert Zivadinov},
  journal={Journal of Neurology},
Cognitive impairment (CI) may occur in clinically isolated syndrome (CIS) patients. While the relationship between CI and magnetic resonance imaging (MRI) has been investigated extensively in multiple sclerosis (MS), MRI correlates of CI in CIS patients are unknown. To investigate the evolution of CI and to determine brain MRI structural correlates associated with CI in CIS patients. This prospective 24-month observational study examined 81 CIS patients treated with 30 µg of intramuscular… CONTINUE READING
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