Longitudinal MR spectroscopic imaging of pediatric diffuse pontine tumors to assess tumor aggression and progression.

@article{Thakur2006LongitudinalMS,
  title={Longitudinal MR spectroscopic imaging of pediatric diffuse pontine tumors to assess tumor aggression and progression.},
  author={Sunitha B Thakur and S Karimi and Ira J Dunkel and Jason A Koutcher and Weizhao Huang},
  journal={AJNR. American journal of neuroradiology},
  year={2006},
  volume={27 4},
  pages={806-9}
}
Two pediatric patients with diffuse pontine tumors underwent MR spectroscopic imaging pre- and postradiation. Choline/creatine (Cho/Cr) and Cho/N-acetylaspartate (NAA) ratios were elevated before treatment, with no MR imaging contrast enhancement. These ratios were further elevated at 2 posttreatment follow-up studies, despite signs of excellent clinical improvement at initial follow-up. This study suggests that MR spectroscopic imaging is more specific in assessing the aggressiveness of… CONTINUE READING