Longitudinal Genome-Wide Association of Cardiovascular Disease Risk Factors in the Bogalusa Heart Study

@inproceedings{Smith2010LongitudinalGA,
  title={Longitudinal Genome-Wide Association of Cardiovascular Disease Risk Factors in the Bogalusa Heart Study},
  author={Erin N. Smith and Wei Chen and Mika K{\"a}h{\"o}nen and Johannes Kettunen and Terho Lehtim{\"a}ki and Leena Peltonen and Olli T. Raitakari and Rany M. Salem and Nicholas J. Schork and Marian Shaw and Sathanur R. Srinivasan and Eric J. Topol and Jorma S. A. Viikari and Gerald Berenson and Sarah S. Murray},
  booktitle={PLoS genetics},
  year={2010}
}
Cardiovascular disease (CVD) is the leading cause of death worldwide. Recent genome-wide association (GWA) studies have pinpointed many loci associated with CVD risk factors in adults. It is unclear, however, if these loci predict trait levels at all ages, if they are associated with how a trait develops over time, or if they could be used to screen individuals who are pre-symptomatic to provide the opportunity for preventive measures before disease onset. We completed a genome-wide association… CONTINUE READING

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