Longitudinal Analysis of Tetanus- and Influenza-Specific IgG Antibodies in Myeloma Patients

@inproceedings{Kobold2012LongitudinalAO,
  title={Longitudinal Analysis of Tetanus- and Influenza-Specific 
IgG Antibodies in Myeloma Patients},
  author={Sebastian Kobold and Tim Luetkens and Britta Marlen Bartels and Yanran Cao and York Hildebrandt and Orhan Sezer and Henrike Reinhard and Julia Templin and Katrin Bartels and Nesrine Lajmi and Friedrich Haag and C Carsten Bokemeyer and Nicolaus Kr{\"o}ger and Djordje Atanackovic},
  booktitle={Clinical & developmental immunology},
  year={2012}
}
BACKGROUND Multiple myeloma (MM) and its therapies may induce a severely compromised humoral immunity. We have performed a longitudinal analysis of IgG-antibody responses against influenza virus (FLU) and tetanus toxoid (TT) as surrogate markers for the B cell-mediated immunity in MM patients. METHODS 1094 serum samples of 190 MM patients and samples from 100 healthy donors were analyzed by ELISA for FLU- and TT-specific antibodies. RESULTS MM patients evidenced lower levels of FLU- and TT… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 27 references

Humoral and cellular immunity to primary H1N1 infection in patients with hematologic malignancies following stem cell transplantation.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation • 2011
View 1 Excerpt

Multiple myeloma.

The New England journal of medicine • 2011
View 1 Excerpt

Seroprotective titers against 2009 H1N1 influenza A virus after vaccination in allogeneic hematopoietic stem cell transplantation recipients.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation • 2011
View 1 Excerpt

Immunoglobulin prophylaxis in hematopoietic stem cell transplantation: systematic review and meta-analysis.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology • 2009
View 1 Excerpt

Longitudinal analysis and prognostic effect of cancer-testis antigen expression in multiple myeloma.

Clinical cancer research : an official journal of the American Association for Cancer Research • 2009
View 1 Excerpt

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