Longifolicin, longicoricin, and gigantetroneninone, three novel bioactive mono-tetrahydrofuran annonaceous acetogenins from Asimina longifolia (Annonaceae).

@article{Ye1996LongifolicinLA,
  title={Longifolicin, longicoricin, and gigantetroneninone, three novel bioactive mono-tetrahydrofuran annonaceous acetogenins from Asimina longifolia (Annonaceae).},
  author={Qing Mei Ye and Doroth{\'e}e Alfonso and Dean R. Evert and Jerry McLaughlin},
  journal={Bioorganic \& medicinal chemistry},
  year={1996},
  volume={4 4},
  pages={
          537-45
        }
}
Sawtehtetronenin from Goniothalamus sawtehii and its Cytotoxicity
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Sawtehtetronenin was found to be cytotoxic to human hepatocellular carcinoma HepG2 and breast cancer MDA-MB231 cells with IC50 values of 79.3+11.9 μM and 108.1+1.5 μM, respectively.
Recent progress on the total synthesis of acetogenins from Annonaceae
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This review emphasizes only the first total synthesis of molecules of contemporary interest and syntheses that have helped to correct structures of annonaceous acetogenins.
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Acetogenins from the Annonaceae family are a group of secondary metabolites, which are considered the most potent group of mitochondrial complex I inhibitors, and their in vitro and in vivo inhibitory activity and apoptosis induction in human tumor lines are reviewed.
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The review work mainly focused on the anticancer activity of Annona muricata, and here is the initiation for the future anticancer drug from the natural source.
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TLDR
Two new monotetrahydrofuran Annonaceous acetogenins have been isolated from the leaves and twigs of Asimina longifolia by the use of the brine shrimp lethality test for bioactivity-directed fractionation.
Gigantetronenin and gigantrionenin: novel cytotoxic acetogenins from Goniothalamus giganteus.
TLDR
Two new monotetrahydrofuran Annonaceous acetogenins each possessing a double bond along the hydrocarbon chain have been isolated from the bark of Goniothalamus giganteus by the use of brine shrimp lethality for bioactivity-directed fractionation.
Corossolone et corossoline, deux nouvelles γ-lactones mono-tétrahydrofuraniques cytotoxiques
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A new halogenated C15 nonterpenoid with a novel carbon framework, named notoryne, has been isolated from the title alga and its structure was established on the basis of spectroscopic and chemical
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Annonin I ( 1) and anonin VI ( 9) were isolated from the seeds of ANNONA SQUAMOSA L. (Annonaceae). The constitution of 1 is identical with that of squamocin, isolated by Fujimoto et al. (8). The
Annonaceous acetogenins: An updated review
The Annonaceous acetogenins are an exciting new class of bioactive natural products whose antitumour, pesticidal and other bioactivities are due to inhibition of electron transport in mitochondria.
Muricatetrocins A and B and Gigantetrocin B: Three New Cytotoxic Monotetrahydrofuran‐Ring Acetogenins from Annona muricata
Extracts from the seeds of Annona muricata yielded three new Annonaceous acetogenins: muricatetrocin A (=
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