Longevity is impacted by growth hormone action during early postnatal period

Abstract

Life-long lack of growth hormone (GH) action can produce remarkable extension of longevity in mice. Here we report that GH treatment limited to a few weeks during development influences the lifespan of long-lived Ames dwarf and normal littermate control mice in a genotype and sex-specific manner. Studies in a separate cohort of Ames dwarf mice show that… (More)
DOI: 10.7554/eLife.24059

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Cite this paper

@inproceedings{Sun2017LongevityII, title={Longevity is impacted by growth hormone action during early postnatal period}, author={Liou Y Sun and Yimin Fang and Amit Patki and Jacob Je Koopman and David B. Allison and Cristal Monique Hill and Michal M. Masternak and Justin Darcy and Jian Wang and Samuel McFadden and Andrzej Bartke}, booktitle={eLife}, year={2017} }