Longer occupancy of opioid receptors by nalmefene compared to naloxone as measured in vivo by a dual-detector system.

@article{Kim1997LongerOO,
  title={Longer occupancy of opioid receptors by nalmefene compared to naloxone as measured in vivo by a dual-detector system.},
  author={Seyun Kim and Henry N. Wagner and Victor Villemagne and P F Kao and Robert F. Dannals and Hayden T. Ravert and Takashi Joh and Rod Dixon and A. C. Civelek},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={1997},
  volume={38 11},
  pages={1726-31}
}
UNLABELLED Surgical procedures usually involve the administration of narcotic drugs as anesthetics or adjuvants. To reverse the effects of anesthesia, opioid antagonists such as naloxone are commonly used. Due to its short lasting effects, patients receiving naloxone must be monitored carefully. Nalmefene, a pure opiate antagonist with a longer duration of action than naloxone, has shown promise in the reversal of opioid anesthesia. METHODS A simple dual-detector positron radiation detector… CONTINUE READING