Longer blood storage is associated with suboptimal outcomes in high-risk pediatric cardiac surgery.

@article{Manlhiot2012LongerBS,
  title={Longer blood storage is associated with suboptimal outcomes in high-risk pediatric cardiac surgery.},
  author={Cedric Manlhiot and Brian W McCrindle and Ines B. Menjak and Hyeamin Yoon and Helen M. Holtby and Leonardo R. Brand{\~a}o and Anthony K. C. Chan and Steven M. Schwartz and Venkatesan Ben Sivarajan and Lynn Crawford-Lean and Celeste Foreman and Christopher A. Caldarone and Glen S. van Arsdell and Colleen E. Gruenwald},
  journal={The Annals of thoracic surgery},
  year={2012},
  volume={93 5},
  pages={1563-9}
}
BACKGROUND The negative effects of long-term storage of allogeneic red blood cells (RBCs) on outcomes in adult cardiac surgery have been established, but evidence of a similar effect in pediatric cardiac surgery is limited. METHODS The weighted average duration of storage for RBC units used in 1,225 pediatric cardiac operations was determined. Operations were divided into high RBC use (more than 4 units or more than 150 mL/kg) or low RBC use. For both categories, associations between storage… CONTINUE READING