Longer and shorter forms of Sendai virus C proteins play different roles in modulating the cellular antiviral response.

@article{Garcin2001LongerAS,
  title={Longer and shorter forms of Sendai virus C proteins play different roles in modulating the cellular antiviral response.},
  author={Dominique Garcin and Joseph P. Curran and Masae Itoh and Daniel Kolakofsky},
  journal={Journal of virology},
  year={2001},
  volume={75 15},
  pages={6800-7}
}
The Sendai virus (SeV) C gene codes for a nested set of four C proteins that carry out several functions, including the modulation of viral RNA synthesis and countering of the cellular antiviral response. Using mutant C genes (and in particular a C gene with a deletion of six amino acids present only in the larger pair of C proteins) and recombinant SeV carrying these mutant C genes, we find that the nested set of C proteins carry out a nested set of functions. All of the C proteins interdict… CONTINUE READING

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