Longer Leukocyte Telomere Length Is Associated with Smaller Hippocampal Volume among Non-Demented APOE ε3/ε3 Subjects

@inproceedings{Wikgren2012LongerLT,
  title={Longer Leukocyte Telomere Length Is Associated with Smaller Hippocampal Volume among Non-Demented APOE ε3/ε3 Subjects},
  author={Mikael Wikgren and T. Karlsson and Johanna Lind and Therese Nilbrink and Johan Hultdin and Kristel Sleegers and Christine van Broeckhoven and G{\"o}ran Roos and Lars-G{\"o}ran Nilsson and Lars Nyberg and Rolf Adolfsson and Karl-Fredrik Norrback},
  booktitle={PloS one},
  year={2012}
}
Telomere length shortens with cellular division, and leukocyte telomere length is used as a marker for systemic telomere length. The hippocampus hosts adult neurogenesis and is an important structure for episodic memory, and carriers of the apolipoprotein E ε4 allele exhibit higher hippocampal atrophy rates and differing telomere dynamics compared with non-carriers. The authors investigated whether leukocyte telomere length was associated with hippocampal volume in 57 cognitively intact… CONTINUE READING
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