Long-term weight loss with sibutramine: a randomized controlled trial.

@article{Wirth2001LongtermWL,
  title={Long-term weight loss with sibutramine: a randomized controlled trial.},
  author={Alfred Wirth and Johan Krause},
  journal={JAMA},
  year={2001},
  volume={286 11},
  pages={1331-9}
}
CONTEXT Treatment of obesity requires long-term therapy, which can be hampered by difficulties in achieving patient compliance. The effectiveness of sibutramine hydrochloride in treating obesity has been shown in randomized controlled trials. OBJECTIVE To compare the effectiveness of 2 distinct sibutramine regimens with each other and with placebo for weight reduction among obese persons. DESIGN Randomized, double-blind, parallel-group placebo-controlled trial from April 1997 to September… CONTINUE READING