Long-term ventilatory support in spinal muscular atrophy.

  title={Long-term ventilatory support in spinal muscular atrophy.},
  author={I S Gilgoff and E J Kahlstrom and Eithne MacLaughlin and Thomas G. Keens},
  journal={The Journal of pediatrics},
  volume={115 6},
Before ethical issues regarding prolonging life in patients with degenerative disease can be considered, the quality of life with medical intervention must be delineated. We have followed 15 patients with spinal muscular atrophy who have been treated with mechanical ventilation. They have received assisted ventilation for an average of 8 years 10 months (range 5 months to 23 years 10 months). Three of the patients required full-time ventilator assistance at the time of initiation of ventilation… CONTINUE READING