Long-term use of gonadotropin-releasing hormone analogs and hormone replacement therapy in the management of endometriosis: a randomized trial with a 6-year follow-up.

@article{Pierce2000LongtermUO,
  title={Long-term use of gonadotropin-releasing hormone analogs and hormone replacement therapy in the management of endometriosis: a randomized trial with a 6-year follow-up.},
  author={S Joanne Pierce and Mehmet R. Gazvani and Roy G. Farquharson},
  journal={Fertility and sterility},
  year={2000},
  volume={74 5},
  pages={964-8}
}
OBJECTIVE To identify the effects of long-term GnRH agonist use (6-24 months), with and without add-back therapy, and spontaneous reversibility of bone mass density (BMD) up to 6 years after treatment. DESIGN A prospective, randomized, long-term follow-up study. SETTING Obstetrics and gynecology department in a university hospital in the United Kingdom. PATIENT(S) Forty-nine symptomatic women with a laparoscopic diagnosis of endometriosis who had been identified for treatment with long… CONTINUE READING