Long-term treatment with romiplostim in patients with chronic immune thrombocytopenia: safety and efficacy.

@article{Kuter2013LongtermTW,
  title={Long-term treatment with romiplostim in patients with chronic immune thrombocytopenia: safety and efficacy.},
  author={David J Kuter and James B Bussel and Adrian Newland and Ross I. Baker and Roger M. Lyons and Jeffrey S Wasser and J E Viallard and Gail Macik and Mathias Rummel and Kun Nie and Susie Jun},
  journal={British journal of haematology},
  year={2013},
  volume={161 3},
  pages={411-23}
}
Romiplostim was effective, safe, and well-tolerated over 6-12 months of continuous treatment in Phase 3 trials in patients with immune thrombocytopenia (ITP). This report describes up to 5 years of weekly treatment with romiplostim in 292 adult ITP patients in a long-term, single-arm, open-label study. Outcome measures included adverse events (including bleeding, thrombosis, malignancy, and reticulin/fibrosis), platelet response (platelet count >50 × 10(9) per litre), and the proportion of… CONTINUE READING
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