Long-term treatment with antioxidants and a program of behavioral enrichment reduces age-dependent impairment in discrimination and reversal learning in beagle dogs

@article{Milgram2004LongtermTW,
  title={Long-term treatment with antioxidants and a program of behavioral enrichment reduces age-dependent impairment in discrimination and reversal learning in beagle dogs},
  author={Norton William Milgram and Elizabeth Head and Steven Curtis Zicker and Candace J Ikeda-Douglas and Heather L Murphey and Bruce A Muggenberg and Christina T. Siwak and P. Dwight Tapp and Stephen R. Lowry and Carl Cotman},
  journal={Experimental Gerontology},
  year={2004},
  volume={39},
  pages={753-765}
}
The effects of long-term treatment with both antioxidants and a program of behavioral enrichment were studied as part of a longitudinal investigation of cognitive aging in beagle dogs. Baseline performance on a battery of cognitive tests was used to assign 48 aged dogs (9-12 years) into four cognitively equivalent groups, of 12 animals per group: Group CC (control food-control environment), group CE (control food-enriched environment); Group AC (antioxidant fortified food-control environment… CONTINUE READING

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